Enhancement of Dopamine Electrochemical Detection with Manganese Doped Crystalline Copper Oxide

Manganese doped crystalline copper oxide (CuO:Mn) and undoped CuO were prepared at room temperature by the hydrothermal method. The complete physico-chemical characterization of materials was performed using X-ray diffraction (XRD), transmission/scanning electron microscopy (TEM/SEM), photoelectron spectroscopy (XPS). Furthermore, their analytical applicability tested in electrochemical experiments for a dopamine assay. According to morphological investigation, had flat structure with nearly straight edges. XRD analysis proved formation phase good crystallinity, while Mn doping determined XPS be around 1 at.%. Under optimized conditions, pH 5.0, CuO:Mn modified electrode (CuO:Mn/SPE) showed high signal oxidation, linear response 0.1–1 µM 1–100 ranges low limit detection 30.3 nM. Five times higher sensitivity manganese comparison sample achieved. developed CuO:Mn/SPE also commercially available pharmaceutical drug results, suggesting that sensor has promising biomedical application potential.